Empowering Africa-based scientists through AI-enabled Structure-Based Drug and Vaccine Discovery
Structural Biology at the Service of Humanity
BioStruct-Africa is a research-driven, community-focused organisation advancing structural biology for drug and vaccine discovery against diseases of particular relevance to Africa.
Through laboratory research, scientific collaboration, and research ecosystem strengthening, we aim to advance therapeutic discovery while building a sustainable network of structural biology expertise across the continent.
Our Current Initiatives
RESEARCH
We use AI-enabled structural biology to investigate molecular mechanisms underlying malaria, schistosomiasis, and drug-resistant bacterial infections.
Our research focuses on parasite nutrient transport and mechanisms of acid resistance in drug-resistant bacteria, using structural insights to guide the discovery of small molecule and nanobody therapeutics and the design of vaccine candidates against schistosomiasis.
TRAINING & WORKFORCE DEVELOPMENT
Over the next decade, we aim to strengthen Africa's scientific ecosystem by integrating hands-on training, access to research infrastructure, and international partnerships.
Our goal is to train 1,000 Africa-based scientists in AI-enabled structural biology, drug discovery, and computational antibody design, alongside 100 scientists in recombinant protein production. By connecting skills, infrastructure, and collaboration, we seek to translate scientific discoveries into advances in diagnostics, drugs, and vaccines.
Funders
