© 2019 by BioStruct-Africa.

Corporate identity number: 802509-6689

    Alfred Nobels allé 27, LGH 1808, 141 52 Huddinge, Sweden

    Tel: +46-720-185-443                  Email: administrator@biostructafrica.org

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    Bridging a technology gap through knowledge transfer and mentoring of Africa-based researchers using cutting-edge techniques in Structural Biology.

    University of Ghana, January 2019.
    What participants say:
     
    For the first time, I believe there is hope for Africa with the hands-on training in Structural Biology organized by BioStruct-Africa at the University of Ghana of which I am a beneficiary. The area of Structural Biology is yet to be exploited by African researchers as researchers lack expertise in this area, making the issue of drug design and development for Neglected Tropical diseases a mirage in Africa.
    The concept of hands-on training by BioStruct-Africa have opened my eyes to protein crystallization and how to resolve the protein structure after crystallization through on-site or remote data collection
    .  
    Dr. Olusola O. Elekofehinti
    (participant from Nigeria)
    Feedback from the Accra Ghana 2019 workshop has been very inspiring!!! Thanks to the Company of Biologist and The Royal Society of Chemistry for funding.

    Latest news

    09.09.2019

               BioStruct-Africa has been empowering Africa-based scientist through structural biology knowledge transfer and                  mentoring. Read the full article : http://journals.iucr.org/s/issues/2019/05/00/yn5057/index.html?fbclid=IwAR11AD            EFE53Vp8_WDmo5VM2dRHiQuwdvjHgODrkNkPjIUg-wXy1JxwvwN0#BB9 

    02.06.2019

              Dr. Emmanuel Nji and others presents: Crystal structures of a Zea mays CMP-sialic acid transporter (CST) apo and in            complex with CMP and functional assays of corn and human CSTs suggest how CMP-sialic acid is translocated                    across Golgi membranes. Read the full article in: 

              https://www.nature.com/articles/s41594-019-0225-y

    16.01.2019:

                  Dr. Emmanuel Nji and others revealed, the ammonium transporter AmtB and the PII signal transduction protein                    GlnZ are  required to inhibit DraG in Azospirillum brasilense. Read the full article in:
              https://www.ncbi.nlm.nih.gov/pubmed/30633437  

     

    14.12.2018:

              BioStruct-Africa has received another grant from The Royal Society of Chemistry-Biology Interface Division for our              Hands-on training workshop in Structural Biology, a tool for sustainable development in Africa to be held in Accra                Ghana on the 28th of January 2019.

     

    23.10.2018:

    BioStruct-Africa received a grant from the Company of Biologist to support our hands-on training workshop in Structural Biology for sustainable development in Africa to be held in Accra Ghana on the 28th of January 2019.

     

    12.10.2018

    Membrane bilayers are made up of a myriad of different lipids that affect membrane proteins, but identifying those specific lipid requirements remains a challenge. Here Dr. Emmanuel Nji (Founder of Biostruct-Africa) and others present an engineered thermal-shift screen which reveals specific lipid preferences of eukaryotic and prokaryotic membrane proteins.

     

    Read the full paper in Nature Communications titled: An engineered thermal-shift screen reveals specific lipid preferences of eukaryotic and prokaryotic membrane proteins.

     

    https://www.nature.com/articles/s41467-018-06702-3

     

    13 September 2018

    "Conjugative transfer of antibiotic resistance plasmid pCW3 in Clostridium perfringens is mediated by the tcp locus. Here, Dr. Traore (Co-founder of Biostruct-Africa) and others identify a wHTH-type protein, TcpK, that is essential for efficient plasmid transfer and interacts with the plasmid oriT region in an unique manner."


    Monash University, Australia media release: 
    https://www.monash.edu/discovery-institute/news-and-events/news/how-bacteria-play-pass-the-parcel-and-help-each-other-evade-antibiotics

     

    Read the full paper in Nature Communications titled Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3.
    https://www.nature.com/articles/s41467-018-06096-2 

    Combating neglected tropical diseases (NTDs) using Structural Biology